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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1000d3037241fdfa0e8b891bf8b93e4e15a1d676ef70e5d50f1eb98bcc2341cb' 
  AND token = 'gvJ+Dv4oSIVtJWmQJAo8Aaser4GOThOD1wKyXE8vaZo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}