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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78e74e9a8d93ed1ae0a8b82ca4bd10b357bf8be819449f865f6cbcdb9a5b1853' 
  AND token = 'sSfZ9QVJ7lPHIQaBspGu1WRIghl7mTMM5S4CqpYcg84=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}