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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27594046d73e72bce72da96c5f193393d5a27ce8ab41254121542982888d1089' 
  AND token = 'icDzTPcUFKelS0tK/np4tK+e78tgO7X3LOByQ4uMmxI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}