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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7bb735bfbd88eabb4777cb448a0d34abd10793c9f9e37e15be4281364638233' 
  AND token = '+FiNp//jlBkigjsT3T7Da6FNrYgh8nhRr0OCEzcXsy4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}