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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0945386ca1c0e602c96ba7fed37fbb35d33fe0ecffab21b7d02d76dd388d5b46' 
  AND token = 'WBjBVrsiruAzjYTMdoyKPmlECsxew6kZ0yZ1VE6CyX4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}