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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78211731131e0476870ce683d19ac6de799dff25e37b83d403b23dc6334d9c50' 
  AND token = 'jv6RUwPf2ZE+ESheJ5P2V1+8yokbnCpDwGhyGg9h88Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}