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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b38a4e382348a0b33a7c58699f254f6f11125f28f0e515e9678c1a01732e1cb4' 
  AND token = '1osYPoNeT3J6QYZyVEZBe/30HG+3YXSWASmrxxg+fcc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}