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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4807c51ae49a65da4d7bba46d98f2d86c5be0ec9ed9f9d78a3c4e92edcdb9d6' 
  AND token = 'NHAMFCBDbnUlcsz3SQzs4e07zISdhZfsbUkULosG+oI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}