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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '70378d2d540c7e50fee25ed3387eb85c2ecacc217448ef216611ce852f19fa06' 
  AND token = 'Vwq+L1x4b61iXEtqwwbZAjW4ZB/sel/hs/zgrnTlTeU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}