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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43622cebda67ceb8b2eaa90f26bb48434c88ee355a5b2f6b7e4207288cdfd4b0' 
  AND token = 'uIPkurV4BYzKkypwO2heYaWgLLnXdYtyRvkav/dX43Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}