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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d928a19f932e01578f6b4638674257d0de2a94602f6b1dba25e151aa6f82526' 
  AND token = 'BAw5akCFJSjEqFOvOB+WuwTEtIWRk+1xDXuxrfHZjjc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}