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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2cda4e6216ad50da98da6e9294ab0c94f9778225dcaf62ec556e63ae5ab4819' 
  AND token = 'PBk2Qx1Yzs9IzP3RLxw1knEoBvW+j2FvKQoTAz7Y/xY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}