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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb3cd2d381aaf6939d8e50b2d227d01f1c083a2ab0ff77cada86da190d8b348b' 
  AND token = 'QgQHjyQ+Gr21U9rLpU9zTkbgm3Zvx6uepDEPvJaqji4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}