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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'edffc49a070f9cf6f671d16d35b4206cce5ee3e63825f2f42f23de9d2ddfc4f6' 
  AND token = 'rplmCjIBcrHDzmCCsxs8NNCrZck3LGa32r7qHZcQ0CA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}