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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6cbf59ce2459f4832a2b268b3945115da08301a963d06b53122c46c6d1c882b5' 
  AND token = '+HWpWZAhR8M6aEArIsOhxdNXPseb8mfMMmm0sr9jYUo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}