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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25f0c9df670b6739cd372300dfb0026bdc3ee54df496cf625666546128342499' 
  AND token = 'UOunMODPiTRyrMN4xI80NqM4QsR/tRWhTf/eLQJB+MA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}