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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00007fdf0a33ed9fa71871d1ba2464cca5e413fc148b5f3647c809ff2bcc4571' 
  AND token = 'MMVPmfznIBkA2IS8/dSPtoo0ao8prDMFSXqLVtOeH40=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}