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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20b139c68b2922b00940d64f04ef9a2a51133abb9e4c71cf3135c5250bd2ffc1' 
  AND token = 'w0bDsY6xv3iwFG6FasoYLolAZQc4IlbsKT5j5XI1WAs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}