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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1b37e0302e4dd65236898d07557fb6f416104bbb09461e02221ae60a0b871d6' 
  AND token = 'pUsP8C17wS/8Ew3+BS67RtLEdqRzT/c/sRpY48N3wPo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}