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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '767f8f6d767d49a55518efb63f1ae159750fc2f5b3ea0d4f5e25e8f996d5d003' 
  AND token = 'QYKVFUWINpVa+NWdb4/2jopmEXFS+3stOIi/IodYx14=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}