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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c235ec7f71c49734f1eec1ddf94f1501a094c12eb87a24169845ad249200ce26' 
  AND token = 'jqjuPvNJ2W0jas/CJjMK3k8oqa2Vb+oxMNOOiYuh/Ck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}