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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c1ee57146e50d6a8255444c23eacb1323b0ff04055d9db448391980d52e77a0' 
  AND token = 'oVP0oTVBWpb/7Bn2gEfOgl4PlA35YqQ1+X3c+4qXhDE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}