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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d3739610846a15866bb17638c945dae47c6226879ed8a0216186d1ef473a788' 
  AND token = 'Pu/TNiY4T47ufS98D/tFzYmemZCdivgwG7AbInYCSMw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}