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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e506f007e46641926d1705a04f953baad58d07c77f40c5a938c29868ff088e67' 
  AND token = 'G9Q2tH7NINv6xThyr1m0Mtdu1O/0IMmZlIc3Y3YSnpU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}