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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54c0c8d8c4fa627a64c4f5e4b8510276d0e2821395c8b580789416b49208b556' 
  AND token = 't/CG4e+KhrVV4Zw1M0irRnI6/erecQWwYOxZrrmhYPU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}