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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95b1db9403a825254a188e037bdb8e6577a8931ce89dee0d9d8d55594470fed4' 
  AND token = 'ZUD5tZGeF2/zZ/r8vZPCczhm3vE+C07THjO9NJl2Cyk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}