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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6c56d0a834c418a2f41c6afb210d57c7b0efae241248c14c86aaf0f1e372331' 
  AND token = 'a2jtPdTfy1NMOsYJ1Tk4S6HqnvWSwsZCR6r9FcqdOFo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}