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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7d7ebe92bed045f63cc25274a4e8d3e3a8e73e1f9ed01e10f37598336feaceb' 
  AND token = 'GfY2XD0USqCe+ihHhALTyIN/dYupk0uHz6VDHqmPk3Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}