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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be814b2477e0f4e685edce545e05a609eb0afcf07463a8cda7178f6b04d8145d' 
  AND token = 'D4FGD+N+Nrw2iAHB7uKRAGTXvyZfIIY1qvDE5iVf72I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}