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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'beee3fc20cccff6104b1c7ca790e9fbdb98f8e7ab689e60b401d6a2460f8aea6' 
  AND token = 'V/YjNBzt/WqirQOaUp1YJxWpEPmLN7jmybGfHg4bA6o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}