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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e919e330e6d8cfd494cb5b8aeee604380b5109ca1e171c41913ba2c4138715a' 
  AND token = '+MAu2u++zUbzt2PM31XEXQ5LrTSbkSeWmU36hFhzxpU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}