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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed69086ba88dec3e992eb122cb38d0c25c9f04de2ddbe5f47e467ee5a372491e' 
  AND token = 'Ui+TXdsRhMtRv4o9AlPukkUU+TJkF25hSU/pytmlXKA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}