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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dcc2a39cd0312857647922ef7795b2a4be194c7c1a4f9f6b3f0b957b03efea41' 
  AND token = 'Lb4ntZxrIFGSc8Neel9LqwR+Yh62CB2ja9ulJcli7eE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}