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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c89405cb49f1f9dcf47e538d481ad008d146b67378a8bd24a78244c7f2220ebf' 
  AND token = 'qRVUjeafz/472ZyHFYAsT7rT25CgpO6oKMOlbzoP1NA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}