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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '729afe8950dab3cf321ca59838dcc82f8c9e404dc9bc7f8a95640d44583f2517' 
  AND token = 'tiqz1vgNF3jijW261dnXP8+s/OMbu573XGY8NvBgeoo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}