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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54feae5a9da364798c0eec789d96688c9980fcb16950b0abffc7d68a791fc428' 
  AND token = '4Hs+TGpP1b2UuuHZPr4qlNlpAJ68c4jmIt0/RiMasWg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}