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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '780a14220a642c566b6a8f00affcc1dd3d935e8e0e7ca34ae6cd99c3d7652e83' 
  AND token = 'qjcJUkpAVLpJjn/Dkl0NKKyAk5aCTyYoaXeu64LfroM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}