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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3606405c108d46aad4c108e28b89b510cd35b71af67fe481dcd4541462456437' 
  AND token = 'MTfzz6GCWWRBMS2Mt7ClXcKg8qh0oy/s9Z6770w8k3s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}