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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4199d457e6bea38162138e36beb9f30a85a2e59005d0d4b286d3e26a25101f9e' 
  AND token = 'RHmS28jkAXh+eygl/WgfKmMPU7SxCXjWrj2NH11qTC4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}