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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86d21f9ffcc07ecb28786535c7ba06e92802b112d3acd533724de6085757193b' 
  AND token = 'A3KFEkNribjJXdeuu4LMFGJup1emtwVTbPSA+bcz1bw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}