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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b281f1c95358ba96e7e7bd580bf1ad2a61b800b542e918d6097d05826ce6455a' 
  AND token = 'CYzpH/yifNgoJEDP3COOc+/zoLF6NCPxRzxabl94Uco=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}