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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0fe977a61d6e1acb22789de0f8af97455c635cb4e45846cf7e7d2dad1515d6a5' 
  AND token = 'C7Y6snyJmxete2KgWIlfFumFmEAOZ6HXlU66Xpj2Kb0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}