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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '016122748cd0ef2839ec37af4232db5a3654129a7d40c3b2056b8feafc175fd0' 
  AND token = 'BGnZ07omTmqBXA03/KRcXvgse/skgRkg3R++DCtR2z8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}