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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c8e8bb73787846918c48e0699cfab3f81d689f537cb04ff6de2144a01ea14c1' 
  AND token = 'gUt2Y7ddxGebU9X2UP4fHAvZl9uXK2UaVgDWiFlycC8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}