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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ec636cd97186ee6b76f3c1363a10583646c2d478f543038d7dc9c62314b2f0c' 
  AND token = 'ekSM8ldyMiosVQR3THnSbC174tVI5UXw04UIXa3iZrw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}