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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45a280c7e56f93e55447a89ad0c1a1af667215713416702fa38503692cac93b1' 
  AND token = 'LzJ5GrtxqT1AAX5c5SRxPE3LQq+GOB/eBBVRmGUA1UI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}