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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2468c57ff303bb7c9c5bd80e918dff65a66cf4855a7aba0487c898fea4626686' 
  AND token = 'JzAzjjxAqJ3Dwc6WSwjRt4xg1Py1H+9XysBPBp5iw0A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}