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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c02bb6dfdf2a5f560ac67de1fdc31d68cb08d4c2119543192566c8d11e22273' 
  AND token = 'VQAHzWw7iVB3Y2O1tshkvRrZa1+zcXUvoJ7izUkQF9E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}