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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45eaef6bf284ce250a3c794169e0df769f084f8ad54adc5a6040494e71fa020d' 
  AND token = 'yw+ErnbhK1/jRJxErwv/whtQU1/lXGSY7nm/tcsY+XU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}