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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81257ea0f8e19922548ea2df43860b4a3db0c3b5a768706cddf900c47b58c6b4' 
  AND token = 'Ot9xzBywfWFIyQBj3WtsJ5qQD2BB8GPcw3jw7olmz6s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}